Script to reproduce all figures in Chovanec et al.

Chovanec, P., Bolland, D.J., Matheson, L.S., Wood, A.L., Corcoran, A.E. (2018). Unbiased quantification of immunoglobulin diversity at the DNA level with VDJ-seq. Nat. Protoc. 13, 1232–1252.

The R notebook contains R, BASH and python code to reproduce all the analysis starting from fasta (Kaplinsky et al.) or xlxs (Lin et al.) result files. VDJ-seq data available at: GSE106458.

1. Kaplinsky, J. et al. Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cells. Proc. Natl. Acad. Sci. 111, E2622–E2629 (2014).
2. Lin, S. G. et al. Highly sensitive and unbiased approach for elucidating antibody repertoires. Proc. Natl. Acad. Sci. 113, 7846–7851 (2016).