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Extracting SNP annotations
epzjlm edited this page Jan 18, 2024
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If you have genotype data available on the same individuals with methylation profiles you can check for ID mismatches. The methylation arrays have 65 SNPs which can be extracted from the methylation data. These 65 SNPs can be compared to genotypes measured with genotype arrays. You can find more information on how to do this in Sample QC.
You can find a list of snp names here: https://github.com/perishky/meffil/blob/master/docs/snp-names.txt
- Installation
- Sample QC
- Functional normalization
- Functional normalizing separate datasets
- Extracting structural variants
- Estimating cellular composition
- Removing chrX and chrY probes
- Running EWAS
- Extracting CpG annotations
- Extracting SNP annotations
- Extracting detection p-values
- Extracting methylated and unmethylated intensities
- Generate normalization report from normalised betas
- Full pipeline for analysing massive datasets
- Common problems
- Citation