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Multi-compartment model of EAG channels in Drosophila presynaptic terminals

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EAG channels in the pre-synaptic terminal

This repository contains code for a simulation of a presynaptic terminal, where we model a Calcium microdomain using a simple multi-compartment model based off the Hodgkin-Huxley equations.

Installation

Get this repo from within MATLAB using my package manager:

% copy and paste this code in your MATLAB prompt
urlwrite('http://srinivas.gs/install.m','install.m'); 
install sg-s/srinivas.gs_mtools % you'll need this
install sg-s/puppeteer % for manipulation
install sg-s/xolotl % C++ code for simulation
install marderlab/eag % this repository 

or use git if you plan to develop this further:

git clone https://github.com/sg-s/srinivas.gs_mtools
git clone https://github.com/sg-s/puppeteer
git clone https://github.com/sg-s/xolotl
git clone https://github.com/marderlab/eag

Finally, make sure you configure MATLAB so that it is set up to delete files permanently. Otherwise you will end up with a very large number of temporary files in your trash!

Usage

Reproduce the modelling figure by running

paper_figures

in your MATLAB prompt.

License

This software is free software. GPL v3.

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Multi-compartment model of EAG channels in Drosophila presynaptic terminals

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