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GWASPipe

A Python tool, based on GWASLab, for assembling a computational pipeline to standardize, QC, harmonize, convert, and plot your summary statistics.

Requirements

see environment.yml and Makefile

Getting started

The script needs a configuration file, a summary statistics file and its format as input.

e.g.: python src/gwaspipe.py -c examples/config_ldscore_pipe.yml -i ./data/seq.13392.13_res.gwas.regenie.gz -f regenie

Input format can be: regenie, fastgwa, ldsc, fuma

There are some example configuration files in the examples directory.

Reference data

Genome: Genome assembly GRCh37.p13

VCF file with allele frequency information for inferring strand and comparing allele frequency: 1kg_eur_hg19

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