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Diabetes-LFP-Analysis

Written by Zachary Ip ([email protected]) 3/7/23.

This repository is expected to be used in conjunction with spectral-analysis-tools, and utils-toolbox. Code will not run without those repositories on path. This repository was developed in MATLAB, and requires a license with Signal processing toolbox among others.

This code was developed to process a dataset collected by Jialing Liu ([email protected]) and co: Gratianne Rabiller ([email protected]), and Shahram Zarrabian ([email protected] ). This data was collected using control db/+ and type-2 diabetic db/db mice. Data was collected using 16-site linear electrodes. Meta-data and information about the organization of the animals can be found in init_Spk_info.m and init_Synopsis_Dbdb.xlsx.

Raw data begins being processed in notebook_Data_Analysis, and calculated measures are compared in notebook_Statistics. Some values used for the manuscript were calculated by Gratianne Rabiller and stats for those values are calculated in notebook_Statistics_Prism.

Auxiliary test codes notebook_detect_SPWR, notebook_CSD_individual_animals, and notebook_SWR_Spectrogram are not used in final manuscript (as of writing 3/7/23), and were only used during preliminary data analysis.

Final figure generation for the manuscipt (as of writing 3/7/23) are generated in prism by Shahram Zarrabian and Jialing Liu. To facilitate this, notebook_Data_Analysis saves excel files of the final measures to share, however, notebook_Statistics also generates figures in MATLAB.

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